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The reduction in CVD risk among heavy smokers who gave up smoking after 20 pack-years was considerable and occurred within 5 years, supporting the cardiovascular benefit of quitting smoking

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Neurogastroenterol Motil 32:e13789 Yang Y, Yang C, Lei Z, Rong H, Yu S, Wu H, Guo J (2021) Cigarette smoking exposure breaks the homeostasis of cholesterol and bile acid metabolism and induces gut microbiota dysbiosis in mice with different diets