In healthy lungs, airway macrophages rapidly remove apoptotic cells, preventing the release of damage-associated molecular patterns (DAMPs), as well as self-antigens and alarmins, which can cause tissue damage and lead to diseases such as chronic obstructive pulmonary disease (COPD) [29], asthma [30], and COVID-19 [31]
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Light Degradation: Photooxidation can change the primary, secondary, and tertiary structures of proteins and lead to differences in long-term stability, bioactivity, or immunogenicity (19)
Antioxidants like hyaluronic acid and resveratrol were added for extra benefits