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Rapid weight loss draws on lean mass as well as fat, and lean mass is metabolically active tissue you generally want to keep

doi: 10.1007/s40620-013-0002-7

Future studies are expected to explore these benefits further, providing more insights into how tirzepatide could support heart health

Rodbard HW, Jellinger PS, Davidson JA, Einhorn D, Garber AJ, Grunberger G et al (2009) Statement by an American Association of Clinical Endocrinologists/American College of Endocrinology consensus panel on type 2 diabetes mellitus: an algorithm for glycemic control

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However, the precise molecular regulatory mechanisms underlying SAPK2-mediated regulation remain unclear