Gupta R, Debbaneh MG, Liao W
Glutamine and glutamate are closely related amino acids that can interconvert under different conditions
The primary structural difference between PfGST and other GST structures is the presence of an additional loop in the Plasmodium enzyme, connecting the alpha helix 4 to alpha helix 5 (residues 113-120) which are known to be involved in dimer formation and consequently in enzyme activity ( Plasmodium GST and therefore, potential novel antimalarial drugs
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