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Abbreviations AHI Apnea-hypopnea index BMI Body Mass Index CI Confidence interval CPAP Continuous Positive Airway Pressure DBP Diastolic blood pressure DPP-4 Dipeptidyl Peptidase-4 GIP Gastric inhibitory polypeptide GLP-1 Glucagon-like peptide-1 GLP-1 RAs Glucagon-like peptide-1 receptor agonists HbA1c Glycosylated Hemoglobin hsCRP High-sensitivity C-Reactive Protein MD Mean difference OSA Obstructive Sleep Apnea RCTs Randomized controlled trials SBP Systolic blood pressure T2DM Type 2 Diabetes Mellitus Author Contributions All authors contributed to the studys conception and design

Advances in solid-phase synthesis, peptide stapling, cyclization, PEGylation and depot formulations have greatly improved half-life, stability and route of administration

Greaves 2007)

This will allow for the precise control of disease progression at the cellular and organelle levels while minimizing damage to surrounding normal tissues

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LAIR-1 acts as an immune checkpoint on activated ILC2s and regulates the induction of airway hyperreactivity