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Thus, metabolic changes may be key players in many disorders, including depression [91, 92]

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NFAT5, acting as an upstream regulator of Akt1, allows NIK to escape from ubiquitination-mediated degradation when down-regulated by exosomal-miR-93-3p, thereby inhibiting the NF-B2 pathway

Mechanisms of weight-loss plateaus during GLP-1 receptor agonist therapy

Contact your GP if cold sensitivity is severe or persistent, or if accompanied by extreme fatigue, hair loss, unexplained weight gain, breathlessness, or colour changes in hands and feet, as these may indicate thyroid dysfunction, anaemia, or circulatory problems requiring investigation

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