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This mechanism plays a role in activating various downstream pathways, including RAS/MAPK, PI3K/AKT, Wnt/-catenin, and JAK/STAT, which are crucial for controlling a range of cellular physiological activities such as differentiation, proliferation, epithelial cell movement, angiogenesis, and EMT [21]
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Heinrich Caro synthesized Methylene Blue in 1876, originally used as a dye for cotton, wool, and paper
Notoginsenoside Ft1 acts as a TGR5 agonist and an FXR antagonist to combat obesity and insulin resistance