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Retatrutide vs Tirzepatide: Next-Generation Weight Loss Medications Last Updated: February 2026 11 min read Key Takeaways Retatrutide is an investigational triple hormone agonist (GLP-1, GIP, and glucagon) showing 24% average weight loss in trials, while tirzepatide is FDA-approved with proven 21% weight loss

Diese kombinieren durch Nachahmung die Wirkungen von zwei Hormonen: GLP-1 (Glucagon-like Peptide 1) und GIP (glucoseabhngiges insulinotropes Peptid)

These bursts form the fast-acting part of the Ipamorelin and CJC stack