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A score above 2.9 indicates significant insulin resistance

They work through different mechanisms: phentermine is a sympathomimetic that suppresses appetite via norepinephrine release

Medication review becomes essential if diarrhea significantly impacts quality of life or adherence to treatment

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The SURPASS-1 trial investigated the efficacy and safety of the three doses of 5, 10, or 15 mg tirzepatide in drug-nave patients with T2D who were not sufficiently controlled with a lifestyle intervention with diet and exercise versus placebo (70)