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Li Y, Li X, Zheng W, Fan C, Zhang Y, Chen T (2013) Functionalized selenium nanoparticles with nephroprotective activity, the important roles of ROS-mediated signaling pathways
It appears to
10.1016/j.canlet.2020.02.015 52 SuH.PengC.LiuY
10.1093/humrep/deaa366 51 TollH.BergerP.HofmannA.HildebrandtA.OberacherH.LenhofH
Chemical properties Chemical Name: L--glutamyl-L-cysteinyl-glycine Molecular Formula: C10H17N3O6S CAS: 70-18-8 (reduced form) Molecular Weight: 307.32 g/mol Biological Significance Antioxidant Protection In our daily lives, the body constantly produces reactive oxygen species (ROS) and free radicals, which attack cell membranes, proteins, and DNA, causing oxidative stress, accelerating aging, or triggering diseases
AMPK Activation as the Core Mechanism Berberine activates AMP-activated protein kinase (AMPK) in hepatocytes and skeletal muscle, a pathway that overlaps meaningfully with metformin [5]
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