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32,35 Molecular modeling suggested that -helical and -turn conformations near the N-terminus should be energetically comparable for these cross-linked peptides, and that agonist potency was better correlated with computationally predicted -helix propensity than with -turn propensity

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In contrast, the GPXs are involved in the physiological adjustment of peroxide concentrations in the intracellular and extracellular compartments, and are more versatile, so they can also act as scavengers and as repair enzymes

The use of Melanotan 1 is still under investigation and is not yet approved for human consumption as a tanning agent