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Activated STING translocates from the endoplasmic reticulum to the ER-Golgi intermediate compartment and Golgi apparatus, contingent upon the coat protein II (COP II) complex and Arf GTPases

5.1.4 Polymorphisms in autophagy and gut microbiota The risk allele ATG16L1 T300A, a single nucleotide polymorphism (SNP) linked to increased CD risk, leads to dysbiosis in mice, causing an increase in Bacteroides and amplifying the Th1 and Th17 immune responses in the gut lamina propria (160)

doi:10.1080/21505594.2024.2399983 De Angelis M, Mascellino MT, Miele MC, et al

Distinct steady-state properties and TNF responses of epithelial long myosin light chain kinase (MLCK) splice variants

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