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Approximately 83% of orally ingested L-citrulline is converted into L-arginine, via the citrulline-NO cycle (Kerksick, 2018)

doi:10.1016/j.cmet.2016.05.006 Yoshino J, Mills KF, Yoon MJ, Imai SI

Notably, 72% of participants with prediabetes at baseline reverted to normoglycemia during Retatrutide treatment, indicating potential for diabetes prevention in at-risk populations

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