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Furthermore, findings from a mouse model of unilateral ureteral obstruction suggest that NLRP3 promotes TGF- signaling, R-Smad activation, and epithelial-mesenchymal transition in renal tubular epithelial cells through a mechanism independent of its classical inflammasome function [199]

doi: 10.1016/j.ccell.2022.01.002 119 RanGHLinYQTianLZhangTYanDMYuJHet al