Real-time fluorescence quantitative PCR was performed using the 7500 fast real-time PCR System (Applied Biosystems, USA)
What GHK-Cu adds to the formulation: Gene expression modulation across hundreds of genes including collagen genes (Type I, III), tissue inhibitors of metalloproteinases, anti-inflammatory mediators Collagen synthesis stimulation, specifically Type I and Type III collagen the structural proteins of skin, connective tissue, and many other tissues Anti-inflammatory signaling through investigated effects on TNF-, IL-6, and NF-B pathways Copper-peptide chemistry effects including cofactor activity for skin-relevant enzymes Skin-research and hair-research applications (the GHK-Cu literature in these areas is substantial) For the GHK-Cu deep-dive, see Copper Peptides Explained
To facilitate these investigations, the Federal Bureau of Investigation (FBI) launched the Innocence Lost program in 2003
In human Phase 2 clinical trials, doses ranged from 0.3 to 4.5 mg administered once weekly
Bacopa monnieri (100mg) Bacopa monnieri is an aquatic plant related to ashwagandha thats been used for centuries in traditional Ayurvedic medicine
When that evidence matures, I'll update my clinical approach accordingly
