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Lastly, outcomes assessing semaglutide 2-mg once-weekly injection were not included in this study due to the approval of the 2-mg dose occurring toward the end of our study timeframe

This broad spectrum of manifestations reflects the complexity of its pathophysiology, which involves a combination of dopaminergic neuron loss, oxidative stress, alpha-synuclein aggregation into Lewy bodies, mitochondrial dysfunction, neuroinflammation, and disruptions in the gut-brain axis 5,6,7,8,9

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