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Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia

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It's an investigational drug in Phase 3 clinical trials Expected availability: 2027-2028 after FDA approval, assuming Phase 3 trials complete successfully Current access options: Clinical trial enrollment (free), compounding pharmacies with prescription ($200-500/month), or research peptides ($150-500/month) By country: Not approved in US, UK, EU, Australia, or Canada