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doi: 10.1016/j.cell.2012.03.042 18 Brigelius-FloheRMaiorinoM

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Unlike exogenous growth hormone administration, which introduces GH directly into a system in a non-physiological pattern, Ipamorelin functions by stimulating the release of endogenous GH through receptor signaling

Studies on animal and rat models have suggested that MT2 is potentially effective in stimulating the MC4 receptor