Since the medicine goes into the fat and not the muscle, a smaller needle is used
Keep in mind these are from separate and distinct trials, so they arent a direct comparison
This class of drugs is commonly called glucagon-like peptide 1 (GLP-1) agonists
NICE Technology Appraisal (TA875) recommends semaglutide (Wegovy) only for adults with at least one weight-related comorbidity and a BMI 35 kg/m (or 32.5 kg/m for people from South Asian, Chinese, other Asian, Middle Eastern, Black African or African-Caribbean backgrounds)
Although compounding pharmacies could, in theory, create their own microdose GLP-1 pills, it is unclear if these will become available
For a 200 lb patient, thats 40 pounds