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Peptides for Targeting Chondrogenic Induction and Cartilage Regeneration in Osteoarthritis, Liao H.J., Chen H.T., Chang C.H., Journal (Cartilage, September 2024, Epub ahead of print)

Because no published human pharmacokinetic study of this compound exists

For the efficacy estimand, the LSM change in HbA1c from baseline at week 52 as the primary endpoint was 2.24%, 2.43%, and 2.58% with tirzepatide 5, 10, and 15 mg, respectively, versus 1.44% with insulin glargine