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The aspartic acid residue is highly susceptible to dehydration, forming a cyclic imide that can then hydrolyze into either the original form or an inactive iso-aspartate analog

Side effects are typically mild and may include redness or swelling at the injection site, headaches, or digestive discomfort

Bulk Drug Substances Used in Compounding Under Section 503A

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The main reason is that GSH-Au NCs@His does not have the capacity to form an Au-S bond, which greatly reduces the effectiveness of GSH-Au NCs@His to consume GSH, thus protecting tumor cells from ROS oxidative damage (Figure 7C)

The SHREAD gene therapy platform for paracrine delivery improves tumor localization and intratumoral effects of a clinical antibody