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Rather than trying to replace the body's natural processes, our philosophy is to work with them

GLP-1 plays a crucial role in glucose metabolism by enhancing insulin secretion, suppressing glucagon release, delaying gastric emptying, and reducing appetite and food intake

Results from this study for Examples tested are consistent with an extended pharmacokinetic profile

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In ACHIEVE-1 , the first of seven Phase 3 studies in people with type 2 diabetes, orforglipron reduced A1C by an average of 1.3% to 1.6% across doses compared to placebo at 40 weeks, starting from a baseline of 8.0%