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BP, JP, JV, FB, MJ, XS, OO, DW, MG, and HM: writing review and editing

The compound has been a subject of biochemical investigation since its isolation from human plasma in the 1970s

10.1124/jpet.121.000587 31 LiuJ.XiaoQ.XiaoJ.NiuC.LiY.ZhangX.et al (2022)

Key Features High-strength 2500mcg methylcobalamin per ampoule Active form of vitamin B12 Supports energy production and nervous system function Helps maintain healthy vitamin B12 levels Designed for efficient absorption Suitable for IM administration Includes disposable needles and syringes Suitable For Individuals with low vitamin B12 levels Those experiencing tiredness and fatigue associated with B12 deficiency Individuals seeking injectable vitamin B12 supplementation Alternative to oral vitamin B12 supplements Product Information Active Ingredient: Methylcobalamin Strength: 2500mcg per 1ml ampoule Form: Injectable ampoules Administration: Intramuscular (IM) use Expiry Date: 07/2027 Includes disposable needles and syringes

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Mechanistically, BPC-157 activates VEGFR2 via the PI3K-Akt-eNOS axis to promote angiogenesis, stimulates ERK1/2 signalling to enhance fibroblast proliferation and migration, and modulates the NO system to regulate vascular tone