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However, the levels of NADPH and G6PD in the SN (the main affected area of PD) were not examined in the study [117]

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Taken together, these studies underscore that UV radiation-driven activation of ncRNAs forms a multilayered cytoprotective system in melanocytes, orchestrating pigmentation, inflammation control, DNA repair, and survival signaling

Additionally, B12 deficiency affects skin texture , hormone balance , and immune system function, creating cascading health effects that compromise overall wellness

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High refined carbohydrate intake (worsens methyl donor deficiency)