This water-soluble vitamin is an essential component for many physiologic systems within the body, including metabolism and DNA synthesis
Upon exposure to oxidative stress, excessive accumulation of ROS disrupts the structure and function of the cell membrane, alters its permeability, and causes lipid peroxidation, inducing the production of MDA
And since there is no naturally occurring molecular transport system for glutathione to move from our blood plasma to inside our cells, taking it orally, nasally or by injection has very little effect
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Subsequently, the cells were washed with PBS and blocked for 1 h with 1% bovine serum albumin (BSA, Sigma A9418) and 22.52 mg/mL glycine in PBST (PBS + 0.05% Tween-20, LPS Solution CBP007T)