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Chemically similar to glucagon-like peptide-1 (GLP-1), with two amino acid substitutions compared to human GLP-1 (Aib(8), Arg(34)) and derivatized at lysine 26

, Optimization of Co-Agonism at GLP-1 and Glucagon Receptors to Safely Maximize Weight Reduction in DIO-Rodents, Biopolymers 98, no

Graphical Abstract Highlights 1

and, appetite-stimulating NPY/AgRP neurons (75, 77)

While the platforms offer access and affordability, Narula, a practicing cardiologist, said she worries that the platforms do not offer consumers a longstanding relationship with a medical provider and may not provide as much oversight or assistance if a consumer is experiencing side effects of the drugs, for example