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The estimated in vivo redox potential for the GSH/GSSG couple ranges from-260 mV to 150 mV depending on the conditions ( Later on, additional roles for the antioxidant function of GSH have emerged that are strictly related to signal transduction: (i) the interaction of the tripeptide with NO or with RNS (see next section)

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Compared with that of other iGluRs, the activity of NMDARs is inhibited via a so-called Mg 2+ block, which is removed via membrane depolarization (Vargas-Caballero and Robinson, 2004)