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In conclusion, in this large population-based US cohort of adults with diabetes and on metformin, GLP-1RA use was associated with significantly lower risks for AF, compared either with DPP4i or with non-insulin glucose-lowering agents other than SGLT2i

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Beyond its proven benefits in managing obesity and reducing cardiovascular risk, as demonstrated in SELECT Trial [111], Semaglutide also represents an important therapeutic option for CKD in patients with Type 2 DM [29]