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As a result, the insulin-producing cells of the pancreas are overstressed, which can lead to exhaustion of the organ and ultimately to type 2 diabetes [4]

These side effects can sometimes get better over time but, Shah said, at least 10% of patients who start these drugs have to be taken off of them because the side effects do not improve

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The cardiovascular benefits of semaglutide (20% reduction in heart attacks, strokes, and cardiovascular death) substantially outweigh the potential DVT risk