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Characterization of heme as activator of Toll-like receptor 4

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5.4.4 PCs and diabetic foot ulcer Diabetic foot ulcers (DFU) are severe and common complications stemming from a multifactorial interplay of sensory, motor, autonomic, and vascular abnormalities, along with altered foot biomechanics (McDermott et al., 2023)

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In multipotent NPCs, Ngn1, Ngn2, and NeuroD2 retain the closed (H3K27me3) promoter conformation, whereas promoters of Sox4 and Sox11 become open (no H3K27me3