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Predictive biomarkers, particularly those linked to key regulatory axes such as NRF2/p62, COX7A1 or USP13, require urgent discovery and clinical validation to reliably predict sensitivity to ferroptosis inducers or autophagy modulators

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The result is a medication that helps people consume less and burn more energy while also balancing blood sugar and supporting breakdown of fat, which is why it has shown greater weight loss in early studies, says Rhodes