Mistake #5: Eating Too Much Volume Why it's a problem: GLP-1s increase feelings of fullness and slow digestion
The recent JAMA study came about when senior author Bradley J
Orforglipron is the challenger with a different strategy: oral, small-molecule, potentially better for long-term adherence, and easier on the supply chain
The study achieved an unprecedented 90% accuracy in distinguishing individuals with ME/CFS based entirely on these biological markers, definitively proving that gut dysbiosis is a core driver of the disease, not just a secondary symptom
GLP-1s essentially put your fullness signals on steroids, allowing you to feel full sooner and for longer
In rodents, the GLP-1 receptor expression level on thyroid C cells is high, whereas in humans, the expression of the receptor is lower