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Glucagon-like peptide-1 (GLP-1) receptor agonists for headache and pain disorders: a systematic review

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10.1056/NEJMoa1411892 98

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Similar to the transcriptomic changes observed in the hypothalamus, we found that the conjugate prompted transcriptional patterns enriched for functional terms associated with synaptic transmission, including postsynaptic specialization and neuron-to-neuron synapse in the brainstem (Extended Data Fig

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