55 The SURMOUNT Program includes four global phase 3, randomized, placebo-controlled clinical trials with tirzepatide administered subcutaneously once weekly in conjunction with lifestyle intervention.47, 48, 49 There was a substantial degree of weight reduction with 10 mg and 15 mg doses of 18.420.9% in persons with obesity or preobesity (without diabetes), with improvements in cardiometabolic risk factors (Table 2).47, 48, 49 Lower bodyweight reductions of 12.8% and 14.7% with 10 mg and 15 mg doses of tirzepatide, respectively, were observed in persons with preobesity or obesity and T2DM
Tirzepatide injections are easy to administer and nearly painless
Baek JH, Kim SJ, Kang HG, Lee HW, Kim JH, Hwang KA, et al
Progress in elucidating hostmicrobiome and microbially mediated metabolic interactions, together with the advent of multi-omics platforms, is poised to significantly advance mechanistic insights into these multifaceted systems
PlexusDx's Precision Peptide Genetic Test examines variants in peptide receptor pathways (GIPR, GLP1R, MC4R, FTO) that relate to overall metabolic and inflammatory predisposition
The funnel plots were performed to check a part of the reporting bias and a part of the heterogeneity, and there were low risk of the reporting bias and no issues with heterogeneity
