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the effector portion is human, it will interact better with the other parts of the human immune system, e.g., to destroy target cells more efficiently by complement-dependent cytotoxicity (CDC) or antibody-dependent cellular cytotoxicity (ADCC)

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The key difference is strain specificity and manufacturing quality

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Some researchers believe those who have a goal for more significant weight loss may be relatively better candidates for prescription weight loss drugs compared to those with more modest weight loss goals